Same-day stereotactic aspiration and gamma knife treatment for cystic intracranial tumorsKeywords: brain tumor, gamma knife, brain metastasis, cyst, aspirationInteractive Manuscript
Ask Questions of this Manuscript:
What is the background behind your study?
Cystic tumors pose specific treatment challenges due to large volume.
What is the purpose of your study?
To evaluate the efficacy and safty of same-day stereotactic aspiration and Gamma knife radiosurgery (GKRS) for cystic intracranial tumors.
Describe your patient group.
Between 1996 and 2007, 77 patients with cystic intracranial tumor underwent same-day procedure of MRI-guided cyst aspiration followed by GKRS. Sixteen patients underwent biopsy in conjunction with cyst aspiration and GKRS.
Describe what you did.
The diagnoses were metastasis in 43 patients, astrocytoma in 12 patients, vestibular schwannoma in ten patients, craniopharyngioma in nine patients and hemangiopericytoma in three patients.
Describe your main findings.
Symptomatic improvement was achieved in 68 patients (88.3%) immediate after cyst aspiration. The mean tumor volume before and after aspiration were 25.12 cc and 11.11 cc, respectively. There was no treatment related hemorrage, seizure and infection. The mean follow-up period after treatment was 21 months (range, 6-68). Tumor control was achieved in 62 patients (80.5%).
Describe the main limitation of this study.
This was a retrospective series.
Describe your main conclusion.
The same-day stereotactic aspiration and GKRS procedure was safe in patients with cystic brain tumors. Prompt symptom relief was achieved after cyst aspiration.
Describe the importance of your findings and how they can be used by others.
The decrease in tumor volume made the following GKRS more effective with higher prescription dose and lower possibility of radiation side effect.
Cystic tumors pose specific treatment challenges due to large volume.
To evaluate the efficacy and safty of same-day stereotactic aspiration and Gamma knife radiosurgery (GKRS) for cystic intracranial tumors.
Between 1996 and 2007, 77 patients with cystic intracranial tumor underwent same-day procedure of MRI-guided cyst aspiration followed by GKRS. Sixteen patients underwent biopsy in conjunction with cyst aspiration and GKRS.
The diagnoses were metastasis in 43 patients, astrocytoma in 12 patients, vestibular schwannoma in ten patients, craniopharyngioma in nine patients and hemangiopericytoma in three patients.
Symptomatic improvement was achieved in 68 patients (88.3%) immediate after cyst aspiration. The mean tumor volume before and after aspiration were 25.12 cc and 11.11 cc, respectively. There was no treatment related hemorrage, seizure and infection. The mean follow-up period after treatment was 21 months (range, 6-68). Tumor control was achieved in 62 patients (80.5%).
This was a retrospective series.
The same-day stereotactic aspiration and GKRS procedure was safe in patients with cystic brain tumors. Prompt symptom relief was achieved after cyst aspiration.
The decrease in tumor volume made the following GKRS more effective with higher prescription dose and lower possibility of radiation side effect.
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