Same-day stereotactic aspiration and gamma knife treatment for cystic intracranial tumorsXiaomin Liu, MD, PhD1, Zhiyuan Zhang2, Yipei Zhang2, Yanhe Li2, Dong Liu3, Qiang Jia2, Yiguang Lin2, Desheng Xu21Department of Neurosurgery and Gamma Knife Center, 2ND Hospital of Tianjin Medical University 2Gamma Knife Center, 2nd Hospital of Tianjin Medical University, Tianjin, China 3Tianjin, China Keywords: brain tumor, gamma knife, brain metastasis, cyst, aspiration
Cystic tumors pose specific treatment challenges due to large volume.
To evaluate the efficacy and safty of same-day stereotactic aspiration and Gamma knife radiosurgery (GKRS) for cystic intracranial tumors.
Between 1996 and 2007, 77 patients with cystic intracranial tumor underwent same-day procedure of MRI-guided cyst aspiration followed by GKRS. Sixteen patients underwent biopsy in conjunction with cyst aspiration and GKRS.
The diagnoses were metastasis in 43 patients, astrocytoma in 12 patients, vestibular schwannoma in ten patients, craniopharyngioma in nine patients and hemangiopericytoma in three patients.
Symptomatic improvement was achieved in 68 patients (88.3%) immediate after cyst aspiration. The mean tumor volume before and after aspiration were 25.12 cc and 11.11 cc, respectively. There was no treatment related hemorrage, seizure and infection. The mean follow-up period after treatment was 21 months (range, 6-68). Tumor control was achieved in 62 patients (80.5%).
This was a retrospective series.
The same-day stereotactic aspiration and GKRS procedure was safe in patients with cystic brain tumors. Prompt symptom relief was achieved after cyst aspiration.
The decrease in tumor volume made the following GKRS more effective with higher prescription dose and lower possibility of radiation side effect. Project Roles:
X. Liu (), Z. Zhang (), Y. Zhang (), Y. Li (), D. Liu (), Q. Jia (), Y. Lin (), D. Xu ()