GKS for Dural AVFKeywords: dural arteriovenous fistula, gamma knife, cavernous sinus, outcome, radiation-associated tumorInteractive Manuscript
Ask Questions of this Manuscript:
What is the background behind your study?
Sometimes surgery was associated with major morbidity because some locations were not easily accessible. Radiosurgery and endovascular embolization developed.
What is the purpose of your study?
We assess the role of Gamma knife radiosurgery for dural arteriovenous
fistulas and carotid-cavernous fistula (CCF) in role of primary or
secondary treatment after embolization.
Describe your patient group.
Between 1994 and July 2011 we treated 15 patients with dural
arteriovenous fistulas and carotid-cavernous fistula (CCF). 2 patients
were follow up lost. All patients were symptomatic.
Describe what you did.
Before radiosurgery, embolization was performed in 7 patients. The mean patient age was 50 years(19-83). The mean radiation dose to the margin of the angiographically defined fistulas was 19.3 Gy at the 50 % or higher isodose line.
Describe your main findings.
We reviewed the results of clinical follow-up evalutions between 6 and 43 months after radiosurgical treatment. Follow up angiography or MR angiography underwent at least after treatment showed that 77.5 % were totally obliterated . Total obliteration percentage of preGKS embolization group to no embolization group was 87.5: 67. One 57-year-male dural AVF patient developed postradiosurgery complication (radiation associated glioblastoma) after 4 years later.
Describe the main limitation of this study.
This was a retrospective study.
Describe your main conclusion.
Radiosurgery and/ or embolization can provide a useful treatment for Dural arteriovenous fistulas and caroticocavernous fistula(CCF). Radiourgery followed by embolization in selected patients is a safe and effective treatment in selected patients with symptomatic or high risk Dural arteriovenous fistulas.
Describe the importance of your findings and how they can be used by others.
But, radiation-associated astrocytoma can develop after GK radiosurgery
very rarely. We should be suspicious the tumor if the patient''s condition
is worse after Gamma-Knife radiosurgery in dural AVF.
Sometimes surgery was associated with major morbidity because some locations were not easily accessible. Radiosurgery and endovascular embolization developed.
We assess the role of Gamma knife radiosurgery for dural arteriovenous
fistulas and carotid-cavernous fistula (CCF) in role of primary or
secondary treatment after embolization.
Between 1994 and July 2011 we treated 15 patients with dural
arteriovenous fistulas and carotid-cavernous fistula (CCF). 2 patients
were follow up lost. All patients were symptomatic.
Before radiosurgery, embolization was performed in 7 patients. The mean patient age was 50 years(19-83). The mean radiation dose to the margin of the angiographically defined fistulas was 19.3 Gy at the 50 % or higher isodose line.
We reviewed the results of clinical follow-up evalutions between 6 and 43 months after radiosurgical treatment. Follow up angiography or MR angiography underwent at least after treatment showed that 77.5 % were totally obliterated . Total obliteration percentage of preGKS embolization group to no embolization group was 87.5: 67. One 57-year-male dural AVF patient developed postradiosurgery complication (radiation associated glioblastoma) after 4 years later.
This was a retrospective study.
Radiosurgery and/ or embolization can provide a useful treatment for Dural arteriovenous fistulas and caroticocavernous fistula(CCF). Radiourgery followed by embolization in selected patients is a safe and effective treatment in selected patients with symptomatic or high risk Dural arteriovenous fistulas.
But, radiation-associated astrocytoma can develop after GK radiosurgery
very rarely. We should be suspicious the tumor if the patient''s condition
is worse after Gamma-Knife radiosurgery in dural AVF.
Project Roles: