GKS for Neurofibromatosis type 2Mooseong Kim1, Soyoung Ha2, Yoonheok Bae2, Seongjin Jin3, Sunil Lee31 2Inje University Busan Paik Hospital 3Inje University Haeundae Paik Hospital Keywords: neurofibromatosis Type 2, hearing function, vestibular schwannoma, gamma knife, outcome
The goal of radiosurgery is to arrest tumor growth while preserving neurological function. Patients with vestibular schwannomas associated with neurofibromatosis type 2 represent a special challenge because of the risk of complete deafness.
Our purpose was to evaluate the result of stereotactic radiosurgery treating vestibular schwannomas secondary to type 2 neurofibromatosis.
10 patients underwent Gamma knife radiosurgery. 9 patients underwent one
stage radiosurgery, one patient performed two stage radiosurgery.
The mean tumor volume at radiosurgery was 13.3 ml, the mean marginal dose was 10.8 Gy (range 10-12 Gy)
During the mean follow-up period of 54.7 months, 5 tumors (50%) regressed, 2 tumor (20%) remained unchanged, and One patient (10%) grew. New tumor was developed, and repeated radiosurgery was performed in two patients (20%) after radiosurgery. Useful hearing was preserved in 8 (80%) of the patients. Facial nerve function was preserved in the all patients.
This was a retrospective study.
Radiosurgery is a valuable minimally invasive treatment for vestibular schwannomas secondary to type 2 neurofibromatosis.
Hearing preservation results will have to be studied over time to test durability. Project Roles:
M. Kim (), S. Ha (), Y. Bae (), S. Jin (), S. Lee ()