Quality Of Life in Patients With Non-functional Pituitary Tumour After Gamma Knife Radiosurgery

Erica Pik Lai Ho1, Samuel Cheong Lun Leung1

1Queen Elizabeth Hospital, Hong Kong SAR

Keywords: pituitary adenoma, gamma knife, quality of life, radiosurgery, outcome

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       Quality of life outcomes are infrequently reported.
     The aim of this study was to assess the impact of quality of life (QOL) in patients suffering from non-functional pituitary tumour after Gamma Knife radiosurgery.
     The Chinese version of the Short Form 36 was used to conduct the survey. It has 36 items with eight scales: physical functioning (PF), role limitation due to physical problems (RP), bodily pain (BP), general health (GH), vitality (VT), social functioning (SF), role limitation due to emotional problems (RE) and mental health (MH). Higher scores indicate better quality of life.
     The data was collected by telephone interview.
     Total 56 patients completed the questionnaire from 14 Oct 2009 to 26 Oct 2009. The mean scores of the eight scales were compared between the patients and Hong Kong normative data. There were no statistically significant differences in PF, GH, VT, SF and RE. Mental Health was significantly better in the patients than in the general population, while physical functioning and bodily pain of patients was significantly worse than general public (P<0.05).
     This is a retrospective study.
     Further analysis of the impairment of related scales in relationship to clinical condition required further analysis. 
     It also served as a basis for further study on QOL for functional pituitary tumour.


Project Roles:

E. Ho (), S. Cheong Lun Leung ()