Long-term Effects Of Gamma Knife Radiosurgery For Cerebral Arteriovenous MalformationKeywords: arteriovenous malformation, gamma knife, vascular malformation, radiation injury, outcomeInteractive ManuscriptAsk Questions of this Manuscript: What is the background behind your study? What is the purpose of your study?To evaluate the effects and influential factors of gamma knife radiosurgery on cerebral arteriovenous malformations (cAVM). Describe your patient group.Three hundreds and fortyone patients with cAVM treated, after 1995, by Leksell gammaknife were followed up for 3-10 years, and the results were satisfactory. Describe what you did.To analyse these ten data: gender, age, position, haemorrhage, embolism, dosage, volume, energy, method of fixing, time of follow-up. Describe your main findings.Through the binary Logistic regression model, we found the effect of gamma knife radiosurgery on cAVM was correlated with haemorrhage, dosage and time of followup. Among all the case, there are two cases with cyst formation and 15 cases with obstinate cerebral edema, 1 case died due to the procedure. Hemorrhage occurred in 10 cases, among those 3 patients died. Describe the main limitation of this study.This is a retrospective study. Describe your main conclusion.The Gammaknife is an effective method for the treatment of AVM, but was affected by multiple factor. Describe the importance of your findings and how they can be used by others.The complication is relatively rare, however, long time follow-up is necessary. To evaluate the effects and influential factors of gamma knife radiosurgery on cerebral arteriovenous malformations (cAVM). Three hundreds and fortyone patients with cAVM treated, after 1995, by Leksell gammaknife were followed up for 3-10 years, and the results were satisfactory. To analyse these ten data: gender, age, position, haemorrhage, embolism, dosage, volume, energy, method of fixing, time of follow-up. Through the binary Logistic regression model, we found the effect of gamma knife radiosurgery on cAVM was correlated with haemorrhage, dosage and time of followup. Among all the case, there are two cases with cyst formation and 15 cases with obstinate cerebral edema, 1 case died due to the procedure. Hemorrhage occurred in 10 cases, among those 3 patients died. This is a retrospective study. The Gammaknife is an effective method for the treatment of AVM, but was affected by multiple factor. The complication is relatively rare, however, long time follow-up is necessary. Project Roles:
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