Gamma Knife Radiosurgery For Cavernous Hemangiomas Of Cavernous Sinus

Selcuk Peker1, Meric Sengoz1, Necmettin Pamir1

1Acibadem University, Istanbul, Turkey

Keywords: cavernous hemangioma, gamma knife, cavernous sinus, skull base, outcome

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     Cavernous Hemangiomas of Cavernous Sinus (CHCS) are rare intracranial tumors. In the past, resection  was the mainstay of their treatment. More recently, radiosurgery was begun to used in the treatment of CHCS because of its successful use. 
     In this article the authors evaluate the radiological and clinical outcomes in a series of patients in whom Gamma Knife radiosurgery (GKRS) was used to treat CHCS.
     Fourteen patients with CHCS underwent GKRS between 1997 and 2009. Nine of these patients had craniotomy. Five patients were primarily treated with GKRS. 
     The median tumor volume was 7.7 cm3, and the mean follow-up period was 64 months. The median prescription radiation dose was 15 Gy, and the median prescription isodose configuration was 50%.
     There was clinical improvement in 10 patients (71%), a radiologically stable lesion in all patients. On imaging, the schwannomas shrank in 13 patients (92%), remained stable in 1 patient (8%). These results were comparable for primary and adjuvant GKSs.
     This is a retrospective study.
     Gamma Knife radiosurgery is highly effective for the treatment of CHCS.
     It can be used primarily for small sized tumors and as an adjuvant for the tumors which have been subtotally removed.


Project Roles:

S. Peker (), M. Sengoz (), N. Pamir ()