Gamma Knife Radiosurgery For Giant Cell Tumor Of The Petrous Bone: A Case Report

Keywords: skull, gamma knife, skull base, radiosurgery, brain tumor

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     Cranial giant cell tumor is extremely rare and the number of reported cases is no more than sixty.
     We report a case of giant cell tumors of the both side petrous bone, which were managed using gamma knife radiosurgery (GKR).
     The patient was a 17-year-old boy who had been diagnosed as giant cell tumor.
     Three years ago, he underwent transsphenoidal biopsy for sellar and clinoidal mass and the diagnosis was giant cell tumor. After one year, infratemporal fossa approach and tumor removal was also performed for left petrous bony mass, and the histopathological diagnosis was same. After radiation therapy, he was regularly followed up and a new mass at right petrous bone was found and GKR was performed for the lesion.
     Six months after the GKR, the left side tumor progressed. At that time, we also found that the right side tumor reduced in size after GKR. We performed GKR for the left side tumor based on the result of GKR for right side tumor. Same procedure was performed. However, in this time, we did fractionated GKR because the tumor was a big one, and the calculated volume was 24.8cc. Two-day fractionation GKR was done, and a margin dose of 8.0 Gy was prescribed to the 50% isodose line at the tumor border in each day with exact 24- hour-interval.
     This is a retrospective study.
     We report a case of giant cell tumors of the petrous bone, which were managed successfully using GKR.


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