Durability of Carotid EndarterectomyKeywords: carotid artery, outcome, endarterectomy, stroke, ischemiaInteractive Manuscript
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What is the background behind your study?
Carotid endarterectomy has been demonstrated as a low risk treatment for carotid occlusive disease. Some studies have suggested that carotid angioplasty may be a competitive alternative. What has not been fully considered however is the risk of recurrent stenosis following either intervention.
What is the purpose of your study?
The purpose of this study is to provide outcome data and cost analysis of the durability of carotid endaraterectomy.
Describe your patient group.
1,492 sequential patients (a total of 1,649 endarterectomies) at Saint Mary’s Hospital in Rochester, Minnesota from 1988 to 2010 were followed prospectively with carotid ultrasonography on an annual basis.
Describe what you did.
All patients were maintained on antiplatelet therapy postoperatively and all arteriomoties were closed secondarily with a patch graft. Each operation was performed with intraoperative EEG monitoring and selective shunting. Calculation of cost was also performed.
Describe your main findings.
Two thirds of the patients were men and the mean age was 71. The mean follow-up was 15.8 years. Approximately 60% were symptomatic. The 30 day perioperative stroke rate was 0.3% (n=5) and mortality was 0.4% (n=7). The total morbidity and mortality for the entire cohort was under 1.0%. There were 5 cervical hematomas requiring exploration without sequaelae. Five patients (0.3%) developed recurrent stenosis greater than 70%. The cost for carotid endarterectomies is approximately $200-400 less than stenting per procedure.
Describe the main limitation of this study.
This is a retrospective study.
Describe your main conclusion.
This data confirms that carotid endarterectomy is a safe treatment for carotid stenosis with low periprocedural risk.
Describe the importance of your findings and how they can be used by others.
It is also evident that the durability of surgery is excellent with an extremely low risk for recurrent stenosis. When comparing endarterectomy with angioplasty, durability of the intervention needs to be considered health care costs and incidence of carotid occlusive disease.
Carotid endarterectomy has been demonstrated as a low risk treatment for carotid occlusive disease. Some studies have suggested that carotid angioplasty may be a competitive alternative. What has not been fully considered however is the risk of recurrent stenosis following either intervention.
The purpose of this study is to provide outcome data and cost analysis of the durability of carotid endaraterectomy.
1,492 sequential patients (a total of 1,649 endarterectomies) at Saint Mary’s Hospital in Rochester, Minnesota from 1988 to 2010 were followed prospectively with carotid ultrasonography on an annual basis.
All patients were maintained on antiplatelet therapy postoperatively and all arteriomoties were closed secondarily with a patch graft. Each operation was performed with intraoperative EEG monitoring and selective shunting. Calculation of cost was also performed.
Two thirds of the patients were men and the mean age was 71. The mean follow-up was 15.8 years. Approximately 60% were symptomatic. The 30 day perioperative stroke rate was 0.3% (n=5) and mortality was 0.4% (n=7). The total morbidity and mortality for the entire cohort was under 1.0%. There were 5 cervical hematomas requiring exploration without sequaelae. Five patients (0.3%) developed recurrent stenosis greater than 70%. The cost for carotid endarterectomies is approximately $200-400 less than stenting per procedure.
This is a retrospective study.
This data confirms that carotid endarterectomy is a safe treatment for carotid stenosis with low periprocedural risk.
It is also evident that the durability of surgery is excellent with an extremely low risk for recurrent stenosis. When comparing endarterectomy with angioplasty, durability of the intervention needs to be considered health care costs and incidence of carotid occlusive disease.
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